Marketed under the trade names "Equal" and "NutraSweet," aspartame has met the Food and Drug Administration (FDA) requirements as a food additive for the past thirty years, yet the artificial sweetener continues to be a subject of public controversy. Recent concerns have focused on potential neurotoxicity in humans, since its metabolic byproducts are phenylalanine, known to cause brain damage in humans with an inborn inability to metabolize this amino acid, and aspartic acid, an excitatory neurotransmitter (Stegink et al., 1837).